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Lucie H Clapp Selected Research

Prostaglandins I

8/2018Prostanoid EP₂ Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells.
4/2017Prostacyclins have no direct inotropic effect on isolated atrial strips from the normal and pressure-overloaded human right heart.
1/2017Inotropic Effects of Prostacyclins on the Right Ventricle Are Abolished in Isolated Rat Hearts With Right-Ventricular Hypertrophy and Failure.

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Lucie H Clapp Research Topics

Disease

9Pulmonary Arterial Hypertension
01/2021 - 08/2014
7Pulmonary Hypertension
01/2020 - 07/2012
6Septic Shock (Toxic Shock Syndrome)
04/2012 - 02/2005
5Sepsis (Septicemia)
04/2012 - 11/2006
2Pain (Aches)
01/2021 - 01/2019
2Right Ventricular Hypertrophy
01/2017 - 08/2014
2Shock
05/2009 - 01/2007
2Hypotension (Low Blood Pressure)
05/2009 - 11/2006
2Hypersensitivity (Allergy)
10/2007 - 01/2007
1Inflammation (Inflammations)
10/2020
1Obesity
12/2019
1Connective Tissue Diseases (Connective Tissue Disease)
01/2019
1Hypertrophy
01/2017
1Vascular Remodeling
08/2014
1Hypoxia (Hypoxemia)
08/2014
1Diabetes Mellitus
12/2013
1Familial Primary Pulmonary Hypertension
11/2010
1Acute Liver Failure (Fulminant Hepatic Failure)
03/2007
1Critical Illness (Critically Ill)
05/2005
1Hypertension (High Blood Pressure)
11/2003

Drug/Important Bio-Agent (IBA)

9Epoprostenol (Prostacyclin)FDA LinkGeneric
01/2021 - 11/2010
8treprostinilFDA Link
01/2021 - 07/2012
5Adenosine Triphosphate (ATP)IBA
04/2012 - 02/2005
3ProstaglandinsIBA
10/2020 - 08/2018
3Prostaglandins IIBA
08/2018 - 01/2017
2Potassium Channels (Potassium Channel)IBA
01/2021 - 04/2012
2endothelium-dependent hyperpolarization factor (EDHF)IBA
12/2019 - 03/2007
2beraprostIBA
01/2019 - 01/2019
2Iloprost (Ventavis)FDA Link
09/2015 - 07/2012
2CalciumIBA
05/2011 - 10/2007
2PotassiumIBA
05/2011 - 05/2009
2Large-Conductance Calcium-Activated Potassium Channels (Maxi-K Channels)IBA
05/2011 - 11/2003
2KATP ChannelsIBA
05/2009 - 11/2006
2CatecholaminesIBA
10/2007 - 11/2006
2Vasopressins (Vasopressin)IBA
10/2007 - 01/2007
1potassium channel protein TREK-1IBA
01/2021
1Dinoprostone (PGE2)FDA Link
01/2020
1Thromboxane Receptors (Thromboxane Receptor)IBA
12/2019
1Protein Isoforms (Isoforms)IBA
12/2019
1Cyclooxygenase 1IBA
12/2019
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
12/2019
1selexipagIBA
01/2019
1(4- ((5,6- diphenylpyrazin- 2- yl)(isopropyl)amino)butoxy)acetic acidIBA
01/2017
1Vasodilator Agents (Vasodilators)IBA
09/2015
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
07/2015
12- (3,4- dimethoxybenzyl)- 7- (1- (1- hydroxyethyl)- 4- phenylbutyl)- 5- methylimidazo(5,1- f)(1,2,4)triazin- 4 (3H)-oneIBA
08/2014
1Bleomycin (Blenoxane)FDA LinkGeneric
08/2014
1Atrial Natriuretic Factor (ANF)IBA
08/2014
1NitratesIBA
08/2014
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
08/2014
1Neprilysin (Neutral Endopeptidase)IBA
08/2014
1Natriuretic PeptidesIBA
08/2014
1Phosphodiesterase 5 InhibitorsIBA
08/2014
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2013
1Potassium Channel Blockers (Blockers, Potassium Channel)IBA
04/2012
1Tetraethylammonium (Tetraethylammonium Bromide)IBA
05/2011
1Nitric Oxide (Nitrogen Monoxide)FDA Link
05/2011
1TeaIBA
05/2011
1Cyclic AMP (AMP, Cyclic)IBA
11/2010
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
11/2010
1Sulfonylurea ReceptorsIBA
05/2009
1Pharmaceutical PreparationsIBA
05/2009
1Hormones (Hormone)IBA
10/2007
1Norepinephrine (Noradrenaline)FDA LinkGeneric
10/2007
1Therapeutic UsesIBA
10/2007

Therapy/Procedure

3Therapeutics
01/2021 - 08/2014
1Oral Administration
01/2019
1Endarterectomy (Thromboendarterectomy)
04/2017
1Ligation
05/2011
1Controlled Hypotension
05/2011
1Punctures
05/2011